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Taming the Troublemaker: A Guide to Handling Endometritis in Mares


Endometritis, the inflammation of the uterine lining in mares, can be a sneaky foe. It’s caused by various bacteria, with Streptococcus equi subspecies zooepidemicus (BHS) being a common culprit. These bacteria can sometimes be like sleeping saboteurs, existing in a dormant state within the uterus. This makes them difficult to detect and eliminate, leading to breeding difficulties and pregnancy loss for your mare. Traditional diagnostic methods like swabs might miss these hidden threats.

Signs and Symptoms:

  • Culture negative swab
  • Difficulty getting pregnant
  • Early pregnancy loss
  • Vaginal discharge
  • Prolonged heat cycles
  • Lethargy or discomfort

Treatment Options:

  • Antibiotics: Once the bacteria are identified, targeted antibiotics can be used. However, dormant bacteria are like shielded soldiers, resisting antibiotics because they’re not actively multiplying.
  • Uterine lavage: Flushing the uterus can help remove bacteria and debris.
  • Anti-inflammatory medications: These can help manage discomfort and inflammation.

The Challenge of the Sleeping Saboteurs:

Even with these methods, some mares might continue to struggle due to dormant bacterial infections. This is where innovative solutions like bActivate come into play.


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Our clients experience

bActivate has been tested by the therio group at Hagyard Equine Medical Institute, the world’s largest equine hospital in Kentucky who basically normalized mare fertility by including bActivate into the standard repro work-up.


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  • Success! After 3 years of hardship

    I used bActivate in 2016 and after one covering got a COLT foal in 2017 (after 3 years of hardship ie mare went in foal but never managed to produce a live foal).

    Breeder Mary Davison,
    Cathrinestown Stud Farm, Leixlip, Ireland

  • Potent new tool for the problem mare!

    bActivate enabled us to identify chronically infected mares, which were found to be clean on culture and cytology using routine diagnostics. We will use it for our problem mares in the coming season.

    Drs. Anja Rosenbrock and Meta Osborne, Tinnakill House, Ireland – www.tinnakill.com​

    bActivate is sold and produced by Bojesen and Petersen Biotech ApS

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